Chhavi Sood, Md Ausrafuggaman Nahid, Matthew C. Pahl, Susan E. Doyle, Sarah E. Siegrist (2022) Delta-dependent Notch activation promotes neuroblast temporal patterning and timing of neurogenesis termination in Drosophila. -- Under review.

Noah Dillon, B Cocanougher, Chhavi Sood, Xin Yuan, AB Kohn, LL Moroz, SE Siegrist, M Zlatic, CQ Doe (2022) Single cell RNA-seq analysis reveals temporally-regulated and quiescence-regulated gene expression in Drosophila larval neuroblasts. Neural Development 17(1) | PubMed | PDF

Cami N. Keliinui, Susan E. Doyle, Sarah E. Siegrist (2022) Neural Stem Cell Reactivation in Cultured Drosophila Brain Explants. Journal of visualized experiments:JoVE | PubMed | PDF

Chhavi Sood, Virginia T. Justis, Susan E. Doyle, Sarah E. Siegrist (2022) Notch signaling regulates neural stem cell quiescence entry and exit in Drosophila. Development 149 (4) | PubMed | PDF

Chhavi Sood, Susan E. Doyle, Sarah E. Siegrist (2020) Steroid hormones, dietary nutrients, and temporal progression of neurogenesis. Current Opinion in Insect Science 43, 70-77 | PubMed | PDF

Xin Yuan, Conor W. Sipe, Miyuki Suzawa, Michelle L. Bland, Sarah E. Siegrist (2020) Dilp-2-mediated PI3-kinase activation coordinates reactivation of quiescent neuroblasts with growth of their glial stem cell niche. PLoS Biology 18(5), e3000721 | PubMed | PDF

Sarah E. Siegrist (2019) Termination of Drosophila mushroom body neurogenesis via autophagy and apoptosis Autophagy 15(8), 1481-1482 | PubMed | PDF

Matthew C. Pahl, Susan E. Doyle, Sarah E. Siegrist (2019) E93 Integrates Neuroblast Intrinsic State with Developmental Time to Terminate MB Neurogenesis via Autophagy. Current Biology 29 (5), 750-762 | PubMed | PDF

Conor W. Sipe, Sarah E. Siegrist (2017) Eyeless uncouples mushroom body neuroblast proliferation from dietary amino acids in Drosophila. Elife 6:e26343 | PubMed | PDF

Derek H. Janssens, Danielle C. Hamm, Lucas Anhezini, Qi Xiao, Karsten H. Siller, Sarah E. Siegrist, Melissa M. Harrison, Cheng-Yu Lee (2017) An Hdac1/Rpd3-Poised Circuit Balances Continual Self-Renewal and Rapid Restriction of Developmental Potential during Asymmetric Stem Cell Division. Dev Cell 40(4):367-380 | PubMed | PDF

Susan E. Doyle, Matthew C. Pahl, Karsten H. Siller, Lindsay Ardiff, Sarah E. Siegrist (2017) Neuroblast niche position is controlled by Phosphoinositide 3-kinase-dependent DE-Cadherin adhesion. Development 144, 820-929 | PubMed | PDF

Sarah E. Siegrist, Najm S. Haque, Chun-Hong Chen, Bruce A. Hay, Iswar K. Hariharan (2010) Inactivation of both Foxo and reaper promotes long-term adult neurogenesis in Drosophila. Current Biology 20(7), 643-648 | PubMed | PDF

Sarah E. Siegrist, Chris Q. Doe (2007) Microtubule-induced cortical cell polarity Genes Dev. 2007 Mar1;21(5):4833-96.2019. | PubMed | PDF

Cheng-Yu Lee, Brian D. Wilkinson, Sarah E. Siegrist, Robin P. Wharton, Chris Q. Doe (2006) Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal Dev Cell. 2006 Apr;10(4):441-9. | PubMed | PDF

Sarah E. Siegrist, Chris Q. Doe (2006) Extrinsic cues orient the cell division axis in Drosophila embryonic neuroblasts. Development 133, 529-536 | PubMed | PDF

Sarah E. Siegrist, Chris Q. Doe (2005) Microtubule-induced Pins/Galphai cortical polarity in Drosophila neuroblasts. Cell 123 (7):1323-1335 | PubMed | PDF